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Chien-yi also known as Qian Yi was famous for specializing in treatment children and over the years of treating children he wrote a book entitled "Xiaoer Yaozheng Zhijue" (Key to Therapeutics of Children's Diseases). This book gave detail on the prescription Rehmannia Six Formula (Liuwei Dihuang Wan) which has become the most widely used yin-nourishing prescription by Chinese physicians. His formulation has good remedy effect especially for the elderly despite its origins as a pediatric formulation.
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